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What is mantle cell lymphoma?


Mantle cell lymphoma is a type of cancer that affects a type of white blood cell called a B-lymphocyte. It usually occurs in older adults and can be difficult to treat, but treatments do exist. Mantle cell lymphoma is often found in the bone marrow or spleen, although it can also affect other parts of the body such as the intestines or stomach lining.

What is mantle cell lymphoma?

Mantle cell lymphoma is a type of non-Hodgkin lymphoma that affects the lymph nodes. It’s the most common type of non-Hodgkin lymphoma in people over 60 years old and usually develops slowly, over many years.

Mantle cell lymphoma can spread throughout the body through the bloodstream or bone marrow, but it doesn’t usually spread quickly enough to cause signs or symptoms outside your abdomen (belly) right away–and when it does, they may be hard to notice because they’re similar to those caused by other conditions such as fatigue or weight loss.

Signs and symptoms of mantle cell lymphoma

Mantle cell lymphoma is a cancer of the lymphatic system. It can be hard to diagnose because the symptoms are often vague and come and go, but they include weight loss, fatigue, night sweats, enlarged lymph nodes in your neck or armpits (armpits), fever and chills.

Causes of mantle cell lymphoma

  • Genetic predisposition
  • Environmental factors
  • Viruses (the Epstein-Barr virus and human herpesvirus 6 can cause mantle cell lymphoma)
  • Immune system problems, such as those caused by AIDS or other conditions that weaken the body’s defenses against infection
  • Drugs: certain medications used for cancer treatment may increase the risk for mantle cell lymphoma

Testing for mantle cell lymphoma

If you are diagnosed with mantle cell lymphoma, your doctor will order several tests to determine if it has spread. These tests include:

  • Blood tests. Your doctor will order blood work to check for low levels of platelets, which can indicate that the disease has spread to other organs.
  • Imaging studies (such as CT scans and MRI). These imaging techniques use X-rays or radio waves to create pictures of internal structures in the body. They’re useful for detecting cancerous nodes in the lymph nodes and tumors in other organs such as the liver or spleen. Imaging studies may also be used to evaluate response after treatment has been completed; if there’s no change from one scan to another, your prognosis is good–but if there is any growth seen on follow-up scans after treatment ends then this could indicate poor outcomes from treatment options chosen so far

Treating mantle cell lymphoma

Mantle cell lymphoma is a type of non-Hodgkin’s lymphoma that originates in the mantle zone, a region near the center of your lungs. It can also affect other organs throughout your body, including bone marrow and gastrointestinal tract.

Mantle cell lymphoma is generally treated with chemotherapy drugs such as rituximab (Rituxan), alemtuzumab (Campath) or idelalisib (Zydelig). Radiation therapy is sometimes used to treat this disease as well.

The survival rate for mantle cell lymphoma varies based on where it appears in the body and how advanced it is when diagnosed. A person’s prognosis depends on their overall health before treatment begins; however, most people who are diagnosed with this form of cancer live at least five years after diagnosis because there are so many treatment options available today that allow you to live longer than ever before!


Mantle cell lymphoma is a type of cancer that affects the lymph nodes. It can be difficult to diagnose and treat, but with proper treatment you can live a long and healthy life. The best way to prevent mantle cell lymphoma is by staying healthy through exercise and eating right!

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