News Massive Bio Has Onboarded Over 120,000 Cancer Patients To Find Their Clinical Trial

Navigating New Horizons: Lung Cancer Clinical Trials

Lung cancer often brings many questions, but now there's new hope. Our platform connects you to the latest clinical trials, with a special focus on Stage 3 and Stage 4 (Advanced or Metastatic) lung cancer. We make it easier for patients to find and join these new clinical trials, giving them access to cutting-edge treatments.

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      Find Your Treatment Now

      A Patient Relations Coordinator will reach out to you soon.

      Your personal data is fully confidential and 100% secure

      You can receive a guidebook with information about cancer clinical trials by filling out the form.

      The Latest in Lung Cancer Treatment Options

      Our matching system connects you to new clinical trials and opens a world of potential for those battling lung cancer. Here, you’ll find information on clinical trials for all stages of lung cancer, especially Stage 3 and Stage 4. These trials offer new treatment methods that aren’t yet available to everyone and target the specific biomarker that is causing your cancer diagnosis. This is your chance to get ahead of the disease with us.

      After reviewing your medical records and running the information through our AI powered system, we identify clinical trials you may be eligible for. Not only that, we also provide a concierge service that will allow for a smooth transition into the clinical trial.

      Our team of specialized nurses and physicians will make sure that every detail of your participation in the trial is taken care of before, during and after your enrollment.

      All the services provided are completely free for you and your treating oncologist.

      Understanding the disease
      What is lung cancer?

      It is a type of cancer that begins in the lungs. Like all cancers, it happens when cells in your lungs grow in an uncontrolled way. This growth can then spread to other parts of your body.

      There are two main types of lung cancer:

      • Non-Small Cell Lung Cancer (NSCLC): This is the most common type, making up about 85% of cases. It generally grows and spreads more slowly than the other type. There are several subtypes of NSCLC, including adenocarcinoma, squamous cell carcinoma, and large cell carcinoma.
      • Small Cell Lung Cancer (SCLC): This type accounts for about 15% of lung cancer cases. It grows more quickly and is more likely to spread to other organs in the body.

      Lung cancer grows into nearby areas or spreads to other parts of the body through lymph nodes and the blood. This process, called metastasis, creates new tumors far from the original cancer site. Doctors classify the cancer as stage 3 when it remains near its origin. When it moves to distant places like the brain or bones, they classify it as stage 4.

      NGS testing and clinical trials

      Next-Generation Sequencing (NGS) is vital in linking patients with specific genetic mutations in their cancers to clinical trials for targeted treatments. This approach, part of personalized medicine, increases the effectiveness and success rates of these trials by ensuring patients receive therapies most likely to work for their particular cancer type.

      The genetic mutations are also known as biomarkers, and many are known to be related to the origin of the disease. Some of the more common biomarkers found to cause lung cancer are the following:

      EGFR (Epidermal Growth Factor Receptor) Mutations: These are changes in the EGFR gene found in some types of lung cancer, particularly non-small cell lung cancer (NSCLC). They can indicate a good response to EGFR inhibitors, a type of targeted therapy.

      ALK (Anaplastic Lymphoma Kinase) Rearrangements: This genetic change is found in a small percentage of NSCLC patients. ALK-positive lung cancers can be treated with ALK inhibitors, which are targeted therapies specifically designed to combat this mutation.

      KRAS (Kirsten Rat Sarcoma Viral Oncogene Homolog) Mutations: KRAS mutations are common in NSCLC. They can provide information about prognosis and are currently being studied for targeted therapy options.

      PD-L1 (Programmed Death-Ligand 1) Expression: PD-L1 is a protein that helps keep the immune system from attacking normal cells in the body. High levels of PD-L1 on lung cancer cells might indicate that the cancer could respond well to immunotherapy drugs that target the PD-1/PD-L1 pathway.

      ROS1 Rearrangements: Similar to ALK, ROS1 rearrangements in NSCLC can be targeted by specific inhibitors. Patients with this mutation may respond to therapies targeting the ROS1 protein.

      MET Mutation: This is a less common mutation in NSCLC but can be important for targeted therapy decisions.

      What is the treatment for lung cancer?

      It’s a question asked by many, and the answers are evolving. Lung cancer encompasses several types, with Non-Small Cell Lung Cancer being the most prevalent. Standard treatments vary by stage, with Stage 3 lung cancer often requiring a combination of therapies. Spotting the first signs of lung cancer isn’t always easy, but catching them early can help find the disease sooner and improve treatment success.

      Usual medication used in lung cancer treatment

      In the treatment of lung cancer, a variety of medications are employed, each tailored to the specific type and progression of the disease. Chemotherapy options include well-known drugs such as Cisplatin, Carboplatin, and newer agents like Pemetrexed and Gemcitabine. However, it’s important to consider the potential side effects of these drugs.

      Targeted therapies, which act on specific cellular mechanisms of cancer cells, include Erlotinib and Afatinib, along with ALK inhibitors like Crizotinib and Alectinib. Immunotherapies like Nivolumab and Pembrolizumab boost the body’s immune response to fight cancer cells. Additionally, Bevacizumab, an angiogenesis inhibitor, works by cutting off the blood supply that tumors need to grow. Healthcare providers may use these treatments individually or combine them, forming the foundation of lung cancer drug treatment.

      The Role of Clinical Trials in Lung Cancer

      Clinical trials play a crucial role in the treatment of stage 3 and stage 4 lung cancer for several reasons:

      • Access to New Treatments: Clinical trials offer patients a chance to try new treatments that could work better, especially for serious illnesses like advanced lung cancer, where usual treatments might not work well.
      • Improving Outcomes: By participating in clinical trials, patients contribute to knowledge that could improve survival rates and quality of life for future lung cancer patients.
      • Comprehensive Care: Patients in clinical trials often receive a high level of care and are closely monitored by a dedicated team of healthcare professionals and researchers.
      • Hope for the Future: For many patients with advanced lung cancer, participating in a clinical trial provides hope—both for themselves and the possibility that their participation will help others in the future.
      • Advancing Research: These trials are essential for research, helping scientists understand how new treatments work and for whom they work best. This can lead to the development of more effective treatment strategies and personalized medicine.
      Why Massive Bio?
      Our AI matching tool makes cancer treatment simple.

      We combine the power of technology with our dedicated team of medical providers to find you the best treatment options available.

      How Massive Bio Helps Patients With Lung Cancer

      Massive Bio offers a quick, easy, and FREE way to find clinical trials for patients like you. With our unique clinical trial matching system and compassionate team, Massive Bio can rapidly match you to a clinical trial of a new lung cancer.

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      Dr. Arturo Loaiza Bonilla explains:
      What Are Clinical Trials?

      Cancer is an unfortunate reality that touches most of us at some point in our lives. If you or a loved one has cancer, you may have heard or read that clinical trials could offer access to innovative new treatments. But what exactly is a clinical trial? In this video, Massive Bio co-founder Arturo Loaiza-Bonilla, MD, explains how clinical trials work, what to expect if you enroll in one, and why a clinical trial can be an important treatment option for many cancer patients.


      We dream of the day when cancer disappears from our lives. Massive Bio is working tirelessly on achieving that goal.

      • Why should I trust Massive Bio?

        Why should I trust Massive Bio?

        Massive Bio has provided health to more than 120,000 cancer patients in 25 countries across three continents. It collaborates with over 80 global partners. In 2022, Massive Bio became part of the Precision Cancer Consortium (PCC), alongside major companies such as AstraZeneca, Bayer, Eli Lilly & Company, GSK, Johnson & Johnson/Janssen, Novartis and Roche.

      • What is the process?

        What is the process?

        To find the best clinical research studies for you, we need your medical history and consent. You can provide this consent by filling out the form on this page and the following pages. Once you’ve done that, our patient relations coordinator will contact you to discuss the details and provide further information for clinical research matching report.

      • Why do I have to provide my medical records to enroll in a clinical trial?

        Why do I have to provide my medical records to enroll in a clinical trial?

        To enroll in clinical trial, you must meet highly specific criteria that’s established by the researchers who are conducting the investigation. That includes detailed information about type of cancer, treatment history, response to treatment, and other data that is collected in medical records.

      • What should I do if I don’t have my medical records?

        What should I do if I don’t have my medical records?

        If you are being treated for cancer or any other disease, your doctor should have a complete record of your medical care, including specific information about what form of the disease you have and what treatments you have received. Your patient relations coordinator will contact you and inform you about the details.

      • What are the costs associated with Massive Bio’s services?

        What are the costs associated with Massive Bio’s services?

        Massive Bio provides its services to the patients and their doctors at no cost—you won’t have to pay anything to receive a clinical-research matching report. There are no hidden costs involved.

      • How does Massive Bio protect my personal information?

        How does Massive Bio protect my personal information?

        Massive Bio strictly adheres to all HIPAA guidelines and international regulations focused on maintaining your privacy. We take extra measures to secure your personal information, ensuring it is protected beyond the mandatory requirements.

      • Where can I find clinical research studies in my area?

        Where can I find clinical research studies in my area?

        Your doctor may know of a clinical research study being conducted in your area that’s recruiting participants and is right for you. However, Massive Bio uses its artificial intelligence-powered platform to match patients to clinical research studies of treatments that give you the best chance of a positive outcome and are being conducted in a geographical location that makes sense for you.

      • Can I continue seeing my doctor or oncologist while also taking services of Massive Bio?

        Can I continue seeing my doctor or oncologist while also taking services of Massive Bio?

        Yes, Massive Bio keeps your doctor up to date on your status throughout your participation.