If you have cancer, genomic testing may help your doctor identify genes, proteins, and other biomarkers that could make you a candidate for new therapies or a clinical trial
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Genomic testing is a form of medical exam that analyzes all of a person’s genes. Each human being has about 20,000 genes, which carry the instructions for making the proteins that form our bodies and allow them to function. Collectively, these genes are called the genome. The purpose of genomic testing is to identify any alterations in the genome that can affect health, which are known as biomarkers.
The terms “genomic testing” and “genetic testing” are often used interchangeably, but they are not the same thing. The purpose of a genetic test is to identify alterations, or mutations, in a specific inherited gene. For example, you may have heard of the BRCA gene mutation. An alteration in one form of this gene, known as a BRCA1 mutation, increases the risk for breast and ovarian cancer, as well as certain other malignancies. A mutation in the BRCA2 gene (sometimes called BRCA2 positive) also increases the risk.
Genomic testing is a more complex process that looks not only for inherited mutations, but also for mutations that occur during one’s lifetime, which may be caused by a person’s environment or habits (such as exposure to toxins or smoking). Genomic tests also examine how different genes interact and the proteins they produce, which can all have a significant influence on cancer risk. This process was once costly and time consuming, but technology called next-generation sequencing has made it faster and more affordable.
Patients with biomarker-based cancers may be candidates for targeted therapies that take aim at specific alterations in the genome that promote cancer, or immunotherapies that boost the body’s defenses against the growth and spread of malignant tumors. Patients with certain biomarkers may also be candidates for clinical trials.
A clinical trial is a research study in which scientists evaluate the effectiveness and safety of new medical treatments. That includes new drugs or novel combinations of drugs for treating cancer and other diseases. Every drug approved by the U.S. Food and Drug Administration had to be tested first in clinical trials.
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Access the free matching toolMassive Bio offers a quick, easy, and FREE way to find clinical trials for patients like you. With our unique clinical trial matching system and compassionate team, Massive Bio can rapidly match you to clinical trials of new therapies. If you aren’t sure if you have a biomarker-based cancer, that’s okay. Additional testing can help determine your exact diagnosis.
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Call +1 844 627 7246Clinical trials test the latest scientific advancements in cancer treatment. Patients who choose to enroll in trials can receive cutting-edge treatment and high-quality care under the direction of scientists, doctors, and researchers. Cancer patients can gain access to promising drugs and innovative treatments long before they're made available to the public.
Cancer is an unfortunate reality that touches most of us at some point in our lives. If you or a loved one has cancer, you may have heard or read that clinical trials could offer access to innovative new treatments. But what exactly is a clinical trial? In this video, Massive Bio co-founder Arturo Loaiza-Bonilla, MD, explains how clinical trials work, what to expect if you enroll in one, and why a clinical trial can be an important treatment option for many cancer patients.
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