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Prostate Cancer Clinical trials: Innovation and Hope

Prostate cancer brings up a lot of questions, but there's good news. Our site helps people find new clinical trials for prostate cancer. We make it easy to join these studies, offering new options for treatment.

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      Find Your Treatment Now

      A Patient Relations Coordinator will reach out to you soon.

      Your personal data is fully confidential and 100% secure

      You can receive a guidebook with information about cancer clinical trials by filling out the form.

      The Latest in Prostate Cancer Treatment Options

      Our system links people with prostate cancer to clinical trials, offering more ways to treat and study their cancer. On our platform, you’ll find detailed info about trials for all stages of prostate cancer. These trials have new treatments designed just for your type of prostate cancer. This gives you a way to fight the cancer with our team’s help.

      After checking your medical records and using our AI system, we find clinical trials that you might qualify for. We also offer a concierge service to help you smoothly transition into the clinical trial.

      Our team of nurses and doctors will handle all aspects of your involvement in the trial, from start to finish. All the services provided are completely free for you and your treating oncologist.

      Clinical Trials and Prostate Cancer

      Clinical trials are essential for this cancer treatment for various important reasons:

      Access to Innovative Therapies: Clinical trials give people the chance to try new treatments not yet available to everyone. This is crucial for since existing treatments might not work for everyone.

      Enhancing Treatment Success: Joining a clinical trial can help patients share valuable information that improves treatment methods and life expectancy for others with prostate cancer in the future.

      In-depth Healthcare: Patients in clinical trials get thorough care from a team of healthcare experts and researchers who watch their health closely.

      Creating Hope: Being part of a clinical trial can offer hope to those fighting prostate cancer, both for their own healing journey and for the benefit of others who will face the disease later.

      Pushing Forward Research: Clinical trials are key to advancing medical science. They help researchers figure out how well new treatments work and who is most likely to benefit from them. This can lead to better treatment options and personalized care plans.

      Understanding the disease What is Prostate Cancer?

      Prostate cancer is a type of cancer that occurs in the prostate, a small walnut-shaped gland in males that produces seminal fluid, which nourishes and transports sperm. It’s one of the most common types of cancer in men. Often, prostate cancer grows slowly and is initially confined to the prostate gland, where it may not cause serious harm. However, some types are more aggressive and can spread quickly.

      Main Symptoms and Signs of Prostate Cancer

      Early-stage prostate cancer may not cause symptoms. As it progresses, it can lead to signs and symptoms such as:

      • Difficulty urinating, including a weak or interrupted flow or the need to urinate more often, especially at night.
      • Blood in the urine or semen.
      • Erectile dysfunction.
      • Pain in the hips, back (spine), chest (ribs), or other areas from cancer that has spread to bones.
      • Weakness or numbness in the legs or feet.
      • Loss of bladder or bowel control from cancer pressing on the spinal nerves.

      It’s important to note that these symptoms can also be caused by conditions other than prostate cancer, such as an enlarged prostate. Early detection through screening can be important for identifying prostate cancer at a stage when it’s more likely to be treatable. Regular check-ups and discussions with a healthcare provider about the risks and benefits of prostate cancer screening are recommended for men, especially those over 50 or at higher risk.

      Types of Prostate Cancer

      This type cancer can occur in various forms, with some types being more aggressive than others. The most common types of prostate cancer are categorized based on how the cancer cells look under a microscope and where the cancer starts.

      Here’s an overview of the primary types:

      The vast majority of prostate cancers are adenocarcinomas. These cancers develop from the gland cells (the cells that make the prostate fluid that is added to the semen).

      There are two subtypes of adenocarcinomas:

      • Acinar Adenocarcinoma: Most prostate cancers are of this subtype, starting in the gland cells that line the prostate gland.
      • Ductal adenocarcinoma: Starts in the ducts of the prostate gland. Ductal adenocarcinoma tends to be more aggressive and may cause symptoms more quickly than acinar adenocarcinoma.

      Small Cell Carcinomas
      These are rare and aggressive forms of prostate cancer that start in neuroendocrine cells (hormone-producing cells). Small cell carcinomas tend to grow quickly and are more likely to spread beyond the prostate.

      Squamous Cell Carcinomas
      This rare type of prostate cancer also grows quickly and is more likely to spread. It starts in the flat cells covering the prostate.

      Transitional Cell Carcinomas
      Also known as urothelial carcinomas, these cancers start in the cells that line the urethra (the tube through which urine exits the body). This type of cancer usually starts in the bladder and spreads to the prostate, but it can start in the prostate as well.

      NGS and Prostate Cancer

      Next-Generation Sequencing (NGS) has revolutionized the identification of biomarkers for various cancers, including prostate cancer. NGS can analyze large segments of the genome quickly and accurately, helping to identify genetic mutations, alterations, and other biomarkers that can influence prostate cancer behavior, prognosis, and treatment response.

      For prostate cancer, NGS can identify several types of biomarkers:

      Genetic Mutations

      • BRCA1 and BRCA2: Mutations in these genes are known for their role in breast and ovarian cancers but are also associated with an increased risk of prostate cancer. Men with these mutations may have a more aggressive form of prostate cancer.
      • TMPRSS2-ERG Fusion: A common gene fusion in prostate cancer that can influence the aggressiveness of the cancer.
      • PTEN Loss: PTEN is a tumor suppressor gene, and its loss or mutation can lead to tumor growth and progression.

      Somatic Mutations

      • SPOP, FOXA1, and MYC: Mutations in these genes are associated with prostate cancer development and progression.

      DNA Repair Gene Mutations

      • ATM, CHEK2, and PALB2: Mutations in these genes are involved in DNA repair processes. Like BRCA1/2 mutations, they can suggest sensitivity to certain treatments like PARP inhibitors.
      Why Massive Bio?
      Our AI matching tool makes cancer treatment simple.

      We combine the power of technology with our dedicated team of medical providers to find you the best treatment options available.

      How Massive Bio Helps Patients With Prostate Cancer

      Massive Bio offers a quick, easy, and FREE way to find clinical trials for patients like you. With our unique clinical trial matching system and compassionate team, Massive Bio can rapidly match you to a clinical trial of a new prostate cancer.

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      Dr. Arturo Loaiza Bonilla explains:
      What Are Clinical Trials?

      Cancer is an unfortunate reality that touches most of us at some point in our lives. If you or a loved one has cancer, you may have heard or read that clinical trials could offer access to innovative new treatments. But what exactly is a clinical trial? In this video, Massive Bio co-founder Arturo Loaiza-Bonilla, MD, explains how clinical trials work, what to expect if you enroll in one, and why a clinical trial can be an important treatment option for many cancer patients.


      We dream of the day when cancer disappears from our lives. Massive Bio is working tirelessly on achieving that goal.

      • Why should I trust Massive Bio?

        Why should I trust Massive Bio?

        Massive Bio has provided health to more than 120,000 cancer patients in 25 countries across three continents. It collaborates with over 80 global partners. In 2022, Massive Bio became part of the Precision Cancer Consortium (PCC), alongside major companies such as AstraZeneca, Bayer, Eli Lilly & Company, GSK, Johnson & Johnson/Janssen, Novartis and Roche.

      • What is the process?

        What is the process?

        To find the best clinical research studies for you, we need your medical history and consent. You can provide this consent by filling out the form on this page and the following pages. Once you’ve done that, our patient relations coordinator will contact you to discuss the details and provide further information for clinical research matching report.

      • Why do I have to provide my medical records to enroll in a clinical trial?

        Why do I have to provide my medical records to enroll in a clinical trial?

        To enroll in clinical trial, you must meet highly specific criteria that’s established by the researchers who are conducting the investigation. That includes detailed information about type of cancer, treatment history, response to treatment, and other data that is collected in medical records.

      • What should I do if I don’t have my medical records?

        What should I do if I don’t have my medical records?

        If you are being treated for cancer or any other disease, your doctor should have a complete record of your medical care, including specific information about what form of the disease you have and what treatments you have received. Your patient relations coordinator will contact you and inform you about the details.

      • What are the costs associated with Massive Bio’s services?

        What are the costs associated with Massive Bio’s services?

        Massive Bio provides its services to the patients and their doctors at no cost—you won’t have to pay anything to receive a clinical-research matching report. There are no hidden costs involved.

      • How does Massive Bio protect my personal information?

        How does Massive Bio protect my personal information?

        Massive Bio strictly adheres to all HIPAA guidelines and international regulations focused on maintaining your privacy. We take extra measures to secure your personal information, ensuring it is protected beyond the mandatory requirements.

      • Where can I find clinical research studies in my area?

        Where can I find clinical research studies in my area?

        Your doctor may know of a clinical research study being conducted in your area that’s recruiting participants and is right for you. However, Massive Bio uses its artificial intelligence-powered platform to match patients to clinical research studies of treatments that give you the best chance of a positive outcome and are being conducted in a geographical location that makes sense for you.

      • Can I continue seeing my doctor or oncologist while also taking services of Massive Bio?

        Can I continue seeing my doctor or oncologist while also taking services of Massive Bio?

        Yes, Massive Bio keeps your doctor up to date on your status throughout your participation.