News Massive Bio Has Onboarded Over 200,000 Cancer Patients to Find Their Clinical Trial

Clinical Trials for Pediatric Cancer Treatments

Cancer is tough, but kids are tougher! When regular cancer treatments don't do the trick, clinical trials step in. They're like a new friend in the fight against cancer, bringing hope for better survival and fewer side effects. It's all about giving kids a brighter, healthier future.

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    You can receive a guidebook with information about childhood cancer by filling out the form.

      Find your child's next option now

      A Patient Relations Coordinator will reach out to you soon.

      Your personal data is fully confidential and 100% secure

      You can receive a guidebook with information about childhood cancer by filling out the form.

      What is new in childhood cancer treatment?

      We’re seeing some interesting developments happening in pediatric cancer treatment:

      Immunotherapy: It has shown potential in treating pediatric cancers by leveraging the body’s immune system to target cancer cells.

      Precision Medicine: Tailoring treatments based on the genetic makeup of tumors has gained traction. Identifying specific genetic mutations allows for targeted therapies, potentially reducing side effects and improving outcomes.

      Reducing Side Effects: Efforts are ongoing to minimize the long-term side effects of chemotherapy and radiation. Researchers are exploring novel therapies with fewer adverse effects on growing bodies.

      Targeted Therapies: They aim to block specific molecular pathways of cancer driving tumor growth.

      Collaborative Research: Collaborations among institutions, researchers, and international consortia have accelerated the development of new treatments and clinical trials.

      How Massive Bio can help kids with cancer?
      Massive Bio is working as key members team for kids with cancer:

      Clinical Trial Matching: Our service helps identify innovative treatments that may be more effective or have fewer side effects than standard options. We specialize in matching pediatric cancer patients with suitable clinical trials.

      Personalized Treatment Options: We utilize AI to create personalized treatment plans based on a child’s unique medical profile. This approach may offer targeted therapies tailored to their specific cancer type and genetic makeup.

      Access to Experts: The platform connects families with oncology experts who specialize in pediatric cancers. This access ensures that families receive guidance from specialists who understand the nuances and complexities of treating childhood cancers.

      Navigating Complexities: Managing pediatric cancer can be overwhelming. Massive Bio supports families by providing guidance, resources, and information to navigate the complexities of treatment decisions and available options. If your child is suitable for a clinical trial, we can make this process seamless.

      Continual Support: Massive Bio provides ongoing support, helping families stay informed about the potential opportunities for their child’s care. We also provide concierge services for children who will be enrolling in clinical trials. It includes lodging, accommodation and travel expenses.

      Let’s Learn About Childhood Cancer

      Pediatric cancer refers to cancer that develops in children and adolescents, typically under the age of 18. The most common types of pediatric cancers include:

      Hematologic cancers:

      • Leukemias (cancers of the blood)
      • Lymphomas (lymph nodes cancer)

      Solid Tumors:

      • Brain tumors
      • Neuroblastoma (immature nerve cell cancer)
      • Osteosarcoma (bone cancer)
      • Wilms tumor (kidney cancer), among others.

      Pediatric cancers can differ from adult cancers. They encompass different types of cancers that vary their behavior and response to treatment. Research shows that survival rates for many pediatric cancers have improved significantly in recent years. However, they remain a significant health concern.

      What is an NGS test? Is it important?

      NGS stands for Next-Generation Sequencing, a DNA sequencing technology. It quickly reads millions of DNA pieces together, giving a full look at a person’s genes. They provide detailed genetic information about the cancer cells, allowing for more personalized and targeted approaches to therapy.

      It can help us identify genetic biomarkers. These are specific genetic mutations within cancer cells that can recognize the type of cancer and guide treatment decisions. For instance, certain genetic mutations might indicate a better response to a particular therapy.

      NGS testing is considered part of the standard of care of most cancer types. Discuss this with your child’s oncologist to maximize their possibilities to participate in a clinical trial of interest.

      Did you know about ALK-positive solid tumors in children?

      Anaplastic Lymphoma Kinase (ALK) fusion-positive solid tumors can happen in specific types of cancers. The most recognized ALK positive tumors in pediatric patients include:

      Rhabdomyosarcoma: Is an aggressive type of tumor that arises from soft tissues in the body (muscles, nerves, blood vessels, and fat). They are the most common type of soft tissue sarcoma in childhood, making up half of all such diagnoses in kids. They can manifest anywhere in the body and early symptoms may include swelling or a lump that doesn’t go away.

      Inflammatory Myofibroblastic Tumor (IMT): Is a rare type of cancer characterized by the abnormal growth of certain cells within the body and inflammation. It tends to occur in children and represents 20 percent of all primary lung tumors in this age group. Patients can present with a mass or symptoms including cough, chest pain, abdominal pain, malaise, fever, and weight loss. This disease most commonly affects the lungs, abdomen, pelvis, and retroperitoneum, although it may involve any site.

      Neuroblastoma: Is a type of tumor that predominantly affects children and arises from cells of the sympathetic nervous system. Neuroblastoma primarily affects the adrenal glands but may occur in the abdominal, thoracic, cervical, and pelvic sympathetic ganglia. Its clinical behavior is variable, ranging from spontaneous regression to aggressive metastatic disease.

      Glial Tumors (Low and high grade): Are a diverse group of tumors that arise from cells in the nervous system and usually occur in children and young adults. Experts categorize these tumors broadly into low-grade and high-grade based on their aggressiveness.

      About treatment for pediatric tumors: standard vs. novel therapies

      The standard treatments typically include surgery, chemotherapy, radiation, immunotherapy, and sometimes stem cell transplants. The exact treatment depends on the type and stage of cancer. They aim to eliminate cancer while considering the child’s well-being. Emerging therapies such as immunotherapy and targeted therapies resent the forefront of pediatric cancer research.

      Clinical trials are essential for evaluating the safety and efficacy of these therapies in children and adolescents with cancer. They offer hope for better treatments, improved outcomes, and the advancement of medical knowledge. They provide a pathway to potentially more effective and tailored therapies for children fighting cancer.

      By signing up for our matching program, you’re taking an active role in exploring new possibilities and gaining access to an innovative therapy that can potentially transform your life.

      Why Massive Bio?
      Our AI matching tool makes cancer treatment simple.

      We combine the power of technology with our dedicated team of medical providers to find you the best treatment options available.

      Access the free matching tool

      A Clinical Trial May Be an Option for Your Child

      Massive Bio offers a quick, easy, and FREE way to find clinical research opportunities for children like yours. With our unique clinical research matching system and compassionate team, Massive Bio can rapidly match your child to a clinical research study for those with pediatric cancer.


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      What is a Childhood Cancer clinical trial?

      Clinical trials test the latest scientific advancements in childhood cancer treatment. Patients who choose to enroll in trials can receive cutting-edge treatment and high-quality care under the direction of scientists, doctors, and researchers. Childhood cancer patients might gain access to promising drugs and innovative treatments long before they're made available to the public.

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      You are not alone

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      Dr. Arturo Loaiza Bonilla explains:
      What Are Clinical Trials?

      Cancer is an unfortunate reality that touches most of us at some point in our lives. If you or a loved one has cancer, you may have heard or read that clinical trials could offer access to innovative new treatments. But what exactly is a clinical trial? In this video, Dr. Arturo Loaiza-Bonilla, MD, explains how clinical trials work, what to expect if you enroll in one, and why a clinical trial can be an important treatment option for many cancer patients.



      • Why should I trust Massive Bio?

        Why should I trust Massive Bio?

        Massive Bio has provided health to more than 200,000 cancer patients in 25 countries across three continents. It collaborates with over 80 global partners. In 2022, Massive Bio became part of the Precision Cancer Consortium (PCC), alongside major companies such as AstraZeneca, Bayer, Eli Lilly & Company, GSK, Johnson & Johnson/Janssen, Novartis and Roche.

      • What is the process?

        What is the process?

        To find the best clinical research studies for you, we need your medical history and consent. You can provide this consent by filling out the form on this page and the following pages. Once you’ve done that, our patient relations coordinator will contact you to discuss the details and provide further information for clinical research matching report.

      • Why do I have to provide my medical records to enroll in a clinical trial?

        Why do I have to provide my medical records to enroll in a clinical trial?

        To enroll in clinical trial, you must meet highly specific criteria that’s established by the researchers who are conducting the investigation. That includes detailed information about type of cancer, treatment history, response to treatment, and other data that is collected in medical records.

      • What should I do if I don’t have my medical records?

        What should I do if I don’t have my medical records?

        If you are being treated for cancer or any other disease, your doctor should have a complete record of your medical care, including specific information about what form of the disease you have and what treatments you have received. Your patient relations coordinator will contact you and inform you about the details.

      • What are the costs associated with Massive Bio’s services?

        What are the costs associated with Massive Bio’s services?

        Massive Bio provides its services to the patients and their doctors at no cost—you won’t have to pay anything to receive a clinical-research matching report. There are no hidden costs involved.

      • How does Massive Bio protect my personal information?

        How does Massive Bio protect my personal information?

        Massive Bio strictly adheres to all HIPAA guidelines and international regulations focused on maintaining your privacy. We take extra measures to secure your personal information, ensuring it is protected beyond the mandatory requirements.

      • Where can I find clinical research studies in my area?

        Where can I find clinical research studies in my area?

        Your doctor may know of a clinical research study being conducted in your area that’s recruiting participants and is right for you. However, Massive Bio uses its artificial intelligence-powered platform to match patients to clinical research studies of treatments that give you the best chance of a positive outcome and are being conducted in a geographical location that makes sense for you.

      • Can I continue seeing my doctor or oncologist while also taking services of Massive Bio?

        Can I continue seeing my doctor or oncologist while also taking services of Massive Bio?

        Yes, Massive Bio keeps your doctor up to date on your status throughout your participation.