Publications

Peer-reviewed articles, abstracts, white papers, media, and videos by Massive Bio.
Peer-Reviewed Journal Articles
  • Peer-Reviewed2025
    Empowering Global Hematology-Oncology Education: Assessing the Impact of a Virtual Platform in Combating Educational Inequity
    Leyfman Y., Cortiana V., Balasubramanian M., Menon G.P., Joshi M., Van de Kieft A., Chorya H., Ghazal J., Coloma H.S., Khasawneh G., Gambill J., Park C.H., and Loaiza-Bonilla A. JCO Global Oncology. 2025;11:e2500190.
    DOI: 10.1200/GO-25-00190 View source
    JCO Global Oncology
  • Peer-Reviewed2025
    RadOncRAG: A Novel Retrieval-Augmented Generation Framework Improves Large Language Model Benchmark Performance in Radiation Oncology
    Thaker N.G., Redjal N., Dicker A., Loaiza-Bonilla A., et al.JCO Clinical Cancer Informatics. 2025;9:e2500220. Epub Nov 14, 2025. PMID: 41237352.
    DOI: 10.1200/CCI-25-00220 View source
    JCO Clinical Cancer Informatics.
  • Peer-Reviewed2025
    Harnessing Moravec's Paradox in Health Care: A New Era of Collaborative Intelligence
    Loaiza-Bonilla A., Penberthy S. NEJM AI. 2025;2(5):AIp2500005.
    DOI: 10.1056/AIp2500005 NEJM AI Artificial Intelligence Healthcare Innovation View source
    NEJM AI
  • Peer-Reviewed2026
    A Unified Framework for Pre-Screening and Screening Tools in Oncology Clinical Trials
    Horgan D., Paulson J., Loaiza-Bonilla A., et al. npj Precision Oncology (Nature). 2026.
    DOI: 10.1038/s41698-026-01306-3 Nature Precision Oncology Clinical Trials Artificial Intelligence View source
    npj Precision Oncology (Nature)
  • Peer-Reviewed2026
    Evaluating Multimodal LLMs for Information Extraction from Oncology Reports Requires a Clinically Curated Ground Truth—Two-Phase Evaluation of GPT-4.1 versus GPT-4.0
    Loaiza-Bonilla A., Thaker N.G., Tuysuz E., Yerdan S., Kurnaz S. AI in Precision Oncology. 2026;0(0).
    DOI: 10.1177/2993091X251409792 Precision Oncology Large Language Models Multimodal AI Clinical NLP View source
    AI in Precision Oncology
  • Peer-Reviewed2017
    Feasibility of Precision Oncology Virtual Tumor Boards
    Loaiza-Bonilla A., Kurnaz S., Johnston K., Culcuoglu C., Arango B. Ann Oncol. 2017 Nov 6. Ranked Top 7 article in Annals of Oncology.
    Annals of Oncology
  • ASCO Publications & Abstracts
  • ASCO · JCO2024
    Effect of a novel artificial intelligence (AI)–enabled multi-trial matching system on patient matching using real-world data
    Kurnaz S., Loaiza-Bonilla A., Castañeda D. C, Huner O., Giritlioglu D., Precision Cancer Consortium. J Clin Oncol. 2024;42(16_suppl):e13501.
    DOI: 10.1200/JCO.2024.42.16_suppl.e13501 View source
    JCO (ASCO)
  • ASCO · JCO2025
    Transforming oncology clinical trial matching through multi-agent AI and oncology-specific knowledge graphs: A prospective evaluation in 5,800 patients
    Loaiza-Bonilla A., et al. J Clin Oncol. 2025;43(16_suppl):1554.
    DOI: 10.1200/JCO.2025.43.16_suppl.1554 View source
    JCO (ASCO)
  • ASCO · JCO2025
    Performance evaluation of an AI-powered system for clinical trial matching in oncology
    Leyfman, Y., Loaiza-Bonilla, A., Cortiana, V., Tuysuz, E., Kurnaz, S., Huner, O., Giritlioglu, D., Noel Meza, J. P., & Culcuoglu, C. J Clin Oncol. 2025;43(16_suppl):e13621.
    DOI: 10.1200/JCO.2025.43.16_suppl.e13621 View source
    JCO (ASCO)
  • ASCO · JCO2021
    Outcomes and applicability of a deep learning virtual tumor board (DLVTB) in community-dwelling colorectal cancer (CRC) patients
    Desai, A., Loaiza-Bonilla, A., Culcuoglu, C., Johnston, K., & Kurnaz, S. J Clin Oncol. 2021;39(15_suppl):e18635.
    DOI: 10.1200/JCO.2021.39.15_suppl.e18635 View source
    JCO (ASCO)
  • ASCO GI · Poster2019
    SYNERGY-AI: Artificial intelligence based precision oncology clinical trial matching and registry
    Kurnaz, S., & Loaiza-Bonilla, A. ASCO Gastrointestinal Cancers Symposium; 2019. Poster.
    ASCO GI
  • ASH / Blood Abstracts
  • Conference Abstract2025
    Retrieval-Augmented GPT-4 Improves NCCN-Concordant Lymphoma Treatment Recommendations
    Yost C., Monick S., Loaiza-Bonilla A., et al. Blood (ASH Annual Meeting). 2025;146(Supplement 1):7914.
    DOI: 10.1182/blood-2025-7914 ASH Hematologic Malignancies Artificial Intelligence View source
    Blood (ASH Annual Meeting)
  • White Papers and Technical Reports
  • White Paper / Technical Report2025
    AI in Clinical Trials: An Executable, Equitable Operating System
    Loaiza-Bonilla A, Kurnaz S, Çulcuoğlu ÇM. DPHARM2025; September 2025.
    DPHARM 2025
  • Conference Presentations
  • Conference2026
    AI-Powered Trial Matching for Immune & Cell Therapies: Real-World Validation of an mCODE-Aligned GPT-4o Platform
    Leyfman Y., Loaiza-Bonilla A., et al.Transplantation and Cellular Therapy. 2026;32(2 Suppl):S303–S304.
    Transplantation and Cellular Therapy.
  • Conference2026
    Advancing Equity in Immune & Cell Therapy Education: Global Impact of a Virtual Oncology Platform
    Leyfman Y., Cortiana V., Loaiza-Bonilla A.Transplantation and Cellular Therapy. 2026;32(2 Suppl):S320–S321.
    DOI: 10.1016/j.jtct.2025.12.463 View source
    Transplantation and Cellular Therapy.
  • Conference2025
    ASCO/ESMO Joint Session: Advancing Cancer Research Through Patient-Centric Pre-Screening Hubs Leveraging Digital Technologies
    Loaiza-Bonilla A. ASCO 2025 Annual Meeting; June 3 2025.
    ASCO 2025
  • Conference2025
    PCC Drop-In Session
    Kurnaz S. ASCO 2025 Annual Meeting; May 30 2025.
    ASCO 2025
  • Academic Publications by Co-founders
  • Peer-Reviewed2020
    Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study
    Kuderer NM, Choueiri TK, Shah DP, et al.; Loaiza-Bonilla A, co-author. Lancet. 2020;395(10241):1907-1918.
    The Lancet
  • Peer-Reviewed2021
    Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer
    Grivas P, Khaki AR, Wise-Draper TM, et al.; Loaiza-Bonilla A, co-author. Ann Oncol. 2021;32(6):787-800.
    Annals of Oncology
  • Peer-Reviewed2019
    Effect of gemcitabine and nab-paclitaxel with or without hydroxychloroquine on patients with advanced pancreatic cancer: a phase 2 randomized clinical trial
    Karasic TB, O'Hara MH, Loaiza-Bonilla A, et al. JAMA Oncol. 2019;5(7):993-998.
    JAMA Oncology
  • Editorials & Special Issues
  • Editorial2025
    Guest Editor – Special Issue: The Use of Artificial Intelligence in Predicting Response to Cancer Therapy
    Loaiza-Bonilla A. Cancers (Basel).
    DOI: 10.3390/cancers17213549 Guest Editor Artificial Intelligence Oncology View source
    Cancers (Basel)
  • Media Interviews and Opinion Articles
  • Media · Interview2020
    Authority Magazine Interview with Dr. Selin Kurnaz
    Kurnaz S. Authority Magazine; December 25 2020.
    Authority Magazine
  • Media · Opinion2025
    From Dr Google to AI: Why Moravec's Paradox Still Matters
    Loaiza-Bonilla A. Medscape; May 22 2025.
    Medscape
  • Media · Thought LeadershipOngoing
    Medscape – “Practical AI” Column
    Loaiza-Bonilla A. Medscape. Ongoing expert commentary.
    Artificial Intelligence Clinical Practice Thought Leadership Available here
    Medscape
  • Media · Opinion2022
    Re-engineering Cancer Clinical Trials at Scale
    Kurnaz S. MedCity News.
    MedCity News
  • Industry Publications
  • Industry2020
    In the Search of AI for Oncology
    Culcuoglu CM, Loaiza-Bonilla A. HealthTech Magazines; March 13 2020.
    HealthTech Magazines
  • Video Content and Interviews
  • Video2022
    Age of Artificial Intelligence
    Culcuoglu C. YouTube – Massive Bio Channel; September 27 2022.
    YouTube
  • Video2022
    Massive Future with Our Technology
    Kurnaz S. YouTube – Massive Bio Channel; September 6 2022.
    YouTube
  • Video2024
    Finding Hope in the Battle Against Cancer
    Massive Bio Channel; March 26 2024.
    YouTube
  • Company Publications
  • Company · Magazine2025
    Massive Bio Magazine – Debut Issue
    Massive Bio Magazine; August 2025. Languages: English, Italian, Spanish, Polish, Turkish.
  • Company · Magazine2024
    Massive Bio Magazine – Latest Issue
    Massive Bio Magazine; September 2024. Topics: AI in Cancer Care; Climate Change and Cancer; Clinical Trial Innovations.