Ovarian Granulosa Cell Tumor Clinical Trials

If you have an ovarian granulosa cell tumor, our service provides important support to help you through this challenge. We help patients find the latest clinical trials for ovarian granulosa cell tumors. This makes it easier for them to access advanced options.

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Massive Bio has onboarded over 160,000 cancer patients to find their clinical trial

Our streamlined process simplifies the search for and participation in innovative trials, keeping you informed about the latest developments in healthcare. We are here to support you during this difficult time, providing access to the newest medical research and options while offering guidance every step of the way.

Granulosa cell tumor of the ovary is a rare type of ovarian cancer that originates from granulosa cells, which are involved in egg and hormone production within the ovaries. Although uncommon, these tumors can produce estrogen, leading to distinct effects on the body compared to other ovarian cancers.

Abnormal Uterine Bleeding: Irregular menstrual cycles or bleeding after menopause, often one of the earliest signs.

Abdominal Pain or Distension: As the tumor grows, it can cause discomfort or a noticeable increase in abdominal size.

Hormonal Effects: These tumors may lead to signs of estrogen excess, such as breast tenderness or changes in the endometrial lining, which can cause endometrial hyperplasia or even cancer. In young girls, excess estrogen can trigger early puberty, while in postmenopausal women, it may manifest as symptoms associated with reproductive hormone activity.

Granulosa cell tumors grow slowly. They are low-grade tumors, which means they are less likely to spread compared to more aggressive ovarian cancers. The main treatment is surgery to remove the tumor, and ongoing monitoring is important to check for recurrence. Patients may require additional therapies depending on the stage and characteristics of the tumor.

Granulosa cell tumors (GCTs) of the ovary are staged based on the extent of the disease, which helps determine the best treatment approach and likely prognosis. The main stages are:

Stage I: The tumor is confined to one or both ovaries.

Stage II: The tumor has spread to other pelvic organs, such as the uterus or fallopian tubes.

Stage III: The tumor has spread beyond the pelvis to the abdominal lining or regional lymph nodes.

Stage IV (Metastatic Ovarian Cancer): The tumor has spread to distant organs outside the abdominal cavity, such as the liver or lungs.

Clinical trials are available for Granulosa Cell Tumor patients at all these stages, offering tailored ovarian cancer options that address the unique needs of each stage and type of cancer.

Treated Granulosa Cell Tumor: Refers to a granulosa cell tumor that has undergone medical interventions such as surgery, chemotherapy, or hormone therapy to remove or shrink the tumor. Clinical trials may be available to explore further options or to assess long-term outcomes.

Untreated Granulosa Cell Tumor: Refers to a granulosa cell tumor that has not yet received any form of medical treatment. Clinical trials may offer access to new and potentially more effective options.

Resectable (Surgery-Eligible) Granulosa Cell Tumor: A resectable granulosa cell tumor is one that can be surgically removed. Surgery is often the primary treatment option for resectable tumors and can be curative if the tumor is confined to the ovaries.

Unresectable (Not Surgery-Eligible) Granulosa Cell Tumor: An unresectable granulosa cell tumor is one that cannot be safely removed through surgery. This may be due to the tumor’s size, location, or involvement with critical structures, making surgical removal too risky. In such cases, other treatment options like chemotherapy, hormone therapy, or participation in clinical trials are considered to manage the disease.

Clinical trials play a crucial role for ovarian granulosa cell tumors by evaluating the safety and efficacy of new options, surgical techniques, and diagnostic tools to find more effective and less toxic options, improve quality of life, and increase survival rates for patients. Some of the novel options are:

  • New Chemotherapy Regimens
  • Targeted Trials
  • Immunotherapy Trials
  • Hormone Trials

Option is highly personalized, reflecting the tumor’s characteristics, the patient’s situation, and evolving research in the field. Emerging treatments and clinical trials exploring new chemotherapy regimens, targeted options, and immunotherapies offer additional hope for those affected.

Access to New Options: Participants can access cutting-edge options that are not available outside the clinical trial setting.

Comprehensive and Focused Care: Patients in clinical trials receive dedicated support and close monitoring by specialized healthcare professionals and researchers, ensuring comprehensive management of their condition.

Close Monitoring: Participants in clinical trials receive extensive medical monitoring related to their option and overall health.

Cancer is an unfortunate reality that touches most of us at some point in our lives. If you or a loved one has cancer, you may have heard that clinical trials could offer access to innovative new options. But what exactly is a clinical trial? In this video, Massive Bio co-founder Arturo Loaiza-Bonilla, MD, explains how clinical trials work, what to expect if you enroll in one, and why a clinical trial can be an important option for many cancer patients.

We dream of the day when cancer disappears from our lives. Massive Bio is working tirelessly to achieve that goal.

Exploring Advanced Options for Ovarian Granulosa Cell Tumor

Our streamlined process simplifies the search for and participation in innovative trials, keeping you informed about the latest developments in healthcare. We are here to support you during this difficult time, providing access to the newest medical research and options while offering guidance every step of the way.

Understanding the Disease

What is an Ovarian Granulosa Cell Tumor?

Granulosa cell tumor of the ovary is a rare type of ovarian cancer that originates from granulosa cells, which are involved in egg and hormone production within the ovaries. Although uncommon, these tumors can produce estrogen, leading to distinct effects on the body compared to other ovarian cancers.

Major Signs and Symptoms:

Abnormal Uterine Bleeding: Irregular menstrual cycles or bleeding after menopause, often one of the earliest signs.

Abdominal Pain or Distension: As the tumor grows, it can cause discomfort or a noticeable increase in abdominal size.

Hormonal Effects: These tumors may lead to signs of estrogen excess, such as breast tenderness or changes in the endometrial lining, which can cause endometrial hyperplasia or even cancer. In young girls, excess estrogen can trigger early puberty, while in postmenopausal women, it may manifest as symptoms associated with reproductive hormone activity.

Granulosa cell tumors grow slowly. They are low-grade tumors, which means they are less likely to spread compared to more aggressive ovarian cancers. The main treatment is surgery to remove the tumor, and ongoing monitoring is important to check for recurrence. Patients may require additional therapies depending on the stage and characteristics of the tumor.

Staging of Granulosa Cell Tumor of the Ovary

Granulosa cell tumors (GCTs) of the ovary are staged based on the extent of the disease, which helps determine the best treatment approach and likely prognosis. The main stages are:

Stage I: The tumor is confined to one or both ovaries.

Stage II: The tumor has spread to other pelvic organs, such as the uterus or fallopian tubes.

Stage III: The tumor has spread beyond the pelvis to the abdominal lining or regional lymph nodes.

Stage IV (Metastatic Ovarian Cancer): The tumor has spread to distant organs outside the abdominal cavity, such as the liver or lungs.

Clinical trials are available for Granulosa Cell Tumor patients at all these stages, offering tailored ovarian cancer options that address the unique needs of each stage and type of cancer.

What Does Treated vs. Untreated Granulosa Cell Tumor Mean?

Treated Granulosa Cell Tumor: Refers to a granulosa cell tumor that has undergone medical interventions such as surgery, chemotherapy, or hormone therapy to remove or shrink the tumor. Clinical trials may be available to explore further options or to assess long-term outcomes.

Untreated Granulosa Cell Tumor: Refers to a granulosa cell tumor that has not yet received any form of medical treatment. Clinical trials may offer access to new and potentially more effective options.

What Does Resectable (Surgery-Eligible) and Unresectable (Not Surgery-Eligible) Granulosa Cell Tumor Mean?

Resectable (Surgery-Eligible) Granulosa Cell Tumor: A resectable granulosa cell tumor is one that can be surgically removed. Surgery is often the primary treatment option for resectable tumors and can be curative if the tumor is confined to the ovaries.

Unresectable (Not Surgery-Eligible) Granulosa Cell Tumor: An unresectable granulosa cell tumor is one that cannot be safely removed through surgery. This may be due to the tumor’s size, location, or involvement with critical structures, making surgical removal too risky. In such cases, other treatment options like chemotherapy, hormone therapy, or participation in clinical trials are considered to manage the disease.

What Are the Current Treatment Options for Ovarian Granulosa Cell Tumor?

The treatment options for ovarian granulosa cell tumors, like many other cancers, depend on several factors, including the stage of the tumor, whether it has spread, and the patient’s overall health and fertility desires. Given their rarity and generally low-grade nature, treatment strategies are often individualized. Here’s an overview of the current ovarian tumor treatment options:

Surgery: The cornerstone of treatment for ovarian granulosa cell tumors is surgical removal of the tumor. The extent of surgery can vary:

Unilateral Salpingo-Oophorectomy is the removal of one ovary and its fallopian tube, often used for early-stage tumors while preserving fertility.

Total Hysterectomy with Bilateral Salpingo-Oophorectomy: Removal of both ovaries, fallopian tubes, and the uterus. This is more common in postmenopausal women or cases where fertility preservation is not a concern.

Staging surgery may involve taking samples from lymph nodes and tissues in the pelvis and abdomen. This is done to see how far the disease has spread, especially in advanced cases.

Chemotherapy is used for advanced cases or when there is a high risk of cancer coming back. It is not used as often because tumors usually grow slowly and can be removed with surgery.

Radiation therapy is used less frequently. However, it can be helpful for managing recurring cancer or when surgery does not remove all.

Hormone Therapy: Hormone therapy can be used to slow down tumor growth by blocking estrogen production. Medications like aromatase inhibitors or luteinizing hormone-releasing hormone agonists are often used in hormone therapy.

Granulosa Cell Tumor Clinical Trials

Clinical trials play a crucial role in advancing options for ovarian granulosa cell tumors by evaluating the safety and efficacy of new therapies, surgical techniques, and diagnostic tools to find more effective and less toxic options, improve quality of life, and increase survival rates for patients. Some of the novel options are:

  • New Chemotherapy Regimens
  • Targeted Trials
  • Immunotherapy Trials

Option is highly personalized, reflecting the tumor’s characteristics, the patient’s situation, and evolving research in the field. Emerging treatments and clinical trials exploring new chemotherapy regimens, targeted options, and immunotherapies offer additional hope for those affected.

Benefits of Clinical Trials

Access to New Options: Participants can access cutting-edge options that are not available outside the clinical trial setting.

Comprehensive and Focused Care: Patients in clinical trials receive dedicated support and close monitoring by specialized healthcare professionals and researchers, ensuring comprehensive management of their condition.

Close Monitoring: Participants in clinical trials receive extensive medical monitoring related to their option and overall health.

Dr. Arturo Loaiza Bonilla Explains:

What Are Clinical Trials?

Cancer is an unfortunate reality that touches most of us at some point in our lives. If you or a loved one has cancer, you may have heard that clinical trials could offer access to innovative new options. But what exactly is a clinical trial? In this video, Massive Bio co-founder Arturo Loaiza-Bonilla, MD, explains how clinical trials work, what to expect if you enroll in one, and why a clinical trial can be an important option for many cancer patients.

We dream of the day when cancer disappears from our lives. Massive Bio is working tirelessly to achieve that goal.

How Massive Bio Helps Patients with Granulosa Cell Tumor Cancer
1
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2
Data Collection

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3
Pre Screening

Our expert nurses check clinical trials and contact you

4
Concierge Services

We support you with appointments, travel, and accommodation

Let’s explore your options and bring new hope to your journey.

We offer a quick, easy and FREE way to find ovarian granulosa cell tumor clinical research opportunities for patients like you. With our unique clinical trial matching system (CTMS) and team specialized in oncology, we can rapidly match you to a clinical research study for those diagnosed with ovarian granulosa cell tumor.

[EN] Ads Landing Pages - United States & Canada - English
Let's Explore Your Options
By filling out this form, you're consenting only to release your medical records. You're not agreeing to participate in clinical trials yet.
Frequently asked questions

To enroll in clinical trial, you must meet highly specific criteria that’s established by the researchers who are conducting the investigation. That includes detailed information about type of cancer, treatment history, response to treatment, and other data that is collected in medical records.

If you are being treated for cancer or any other disease, your doctor should have a complete record of your medical care, including specific information about what form of the disease you have and what treatments you have received. Your patient relations coordinator will contact you and inform you about the details.

Massive Bio provides its services to the patients and their doctors at no cost—you won’t have to pay anything to receive a clinical-research matching report. There are no hidden costs involved.

Massive Bio strictly adheres to all HIPAA guidelines and international regulations focused on maintaining your privacy. We take extra measures to secure your personal information, ensuring it is protected beyond the mandatory requirements.

Your doctor may know of a clinical research study being conducted in your area that’s recruiting participants and is right for you. However, Massive Bio uses its artificial intelligence powered platform to match patients to clinical research studies that give you the best chance of a positive outcome and are being conducted in a geographical location that makes sense for you.

Yes, Massive Bio keeps your doctor up to date on your status throughout your participation.