Helping patients find the cholangiocarcinoma
resources they deserve

How do we help Cholangiocarcinoma patients?

Massive Bio offers an independent cancer treatment analysis as well as free clinical trial matching for cholangiocarcinoma patients. Our patient advocates work closely with patients to gather information on their current medical status, and then will provide a list of options from available cancer clinical trials close to your home.

We can also provide a comprehensive cae analysis through our Virtual Tumor Board from cancer specialists. The Virtual Tumor Board (VTB) is comprised of highly specialized oncologists from nationally-recognized Cancer Centers of Excellence. In just 7-10 days after receiving your medical records, we can get you a treatment plan without having to travel far distances and use your valuable time.

Clinical Trials

There are approximately 73 cholangiocarcinoma clinical trials that are currently recruiting patients in the United States right now. With such an extensive list, many of them could be beneficial for you. Our team of patient advocates, who are oncology nurses, and our artificial intelligence based clinical trial matching system will find the best option for you.

Futibatinib Vs Gemcitabine-Cisplatin Chemotherapy as 1st-Line Treatment of Patients With Advanced Cholangiocarcinoma (CCA)

With just a few clicks, you can see your clinical trial matches now. Click here to use our advanced clinical trial match tool.

Cholangiocarcinoma Facts

Cholangiocarcinoma forms in the bile duct and consists of a group of cancer cells. This cancer type is particularly dangerous because it often spreads to the connected tubes in the small intestine, gallbladder, and liver. More often than not, it is not detected until it has spread beyond the bile duct.

Cholangiocarcinoma patients often find out when they experience jaundice, which is the yellowing of one’s eyes and skins.

Despite being difficult to treat, there are only between 2,000 and 3,000 new cases each year, making it one of the more rare cancer types.


Several risk factors have been linked to the development of cholangiocarcinoma. These include, bile duct stones and cysts, being exposed to some chemical toxins commonly used in manufacturing, and a bile duct disease (primary sclerosing cholangitis). Many of the gene mutations that occur and cause the cancerous cells to grow are formed throughout the patient’s life. Other diseases can lead to cholangiocarcinoma as well. These include hepatitis B or C, cirrhosis, irritable bowel syndrome and diabetes. Like other cancer types, excessive alcohol use, smoking, and even obesity can be attributed to the development of cholangiocarcinoma.


The most common form of treatment for cholangiocarcinoma patients are surgery, liver transplant, chemotherapy, radiation therapy, photodynamic therapy, and biliary drainage. Cholangiocarcinoma is a difficult cancer type to treat, so many patients turn to clinical trials for new and innovative treatment options.


Screening methods for cholangiocarcinoma include liver function tests, tumor marker tests, examining your bile duct with a small camera, imaging tests, and a procedure to remove a sample of tissue for testing. After the cancer is found, additional testing often takes place to determine the stage of the cancer. Cholangiocarcinoma has been viewed to be more prevalent in men than women for unknown reasons.


Intrahepatic bile duct cancers
Perihilar bile duct cancers (Klatskin tumors)
Distal (extrahepatic) bile duct cancers


Our team of patient advocates can help guide you to treatment options you might not have been previously aware of. Although you might be new to cancer, we certainly are not. Navigating cancer patients through the tricky path of finding the best treatment is our goal. No two cancer patients are alike, which is why we find treatment for all of our patients based on their specific genomics, location, stage of cancer, and nearly 100 more data points.

    Learn Your Cholangiocarcinoma
    Clinical Trial and Treatment Options