Helping patients find the Myeloproliferative Neoplasm resources they deserve

How do we help patients with Myeloproliferative Neoplasm disorders?

Massive Bio offers an independent cancer treatment analysis as well as free clinical trial matching for patients with Myeloproliferative Neoplasm disorders (MPNs). Our patient advocates work closely with patients to gather information on their current medical status, and then will provide a list of options from available cancer clinical trials close to your home.

We can also provide a comprehensive case analysis through our Virtual Tumor Board from cancer specialists. The Virtual Tumor Board (VTB) is comprised of highly specialized oncologists from nationally-recognized Cancer Centers of Excellence. In just 7-10 days after receiving your medical records, we can get you a treatment plan without having to travel far distances and use your valuable time.

Clinical Trials

There are approximately 110 clinical trials for Myeloproliferative Neoplasm disorders that are currently recruiting patients in the United States right now. With such an extensive list, many of them could be beneficial for you. Our team of patient advocates, who are oncology nurses, and our artificial intelligence-based clinical trial matching system will find the best option for you.

With just a few clicks, you can see your clinical trial matches now. Click here to use our advanced clinical trial match tool.

Myeloproliferative Neoplasm Disorder Facts

Myeloproliferative Neoplasm disorders are rare, slow-growing blood cancers that start in the bone marrow and make abnormal red blood cells, white blood cells, and platelets. There are 6 types of Myeloproliferative Neoplasm disorders:

  • Chronic myelogenous leukemia (CML): A genetic change takes place in the cells that produce red blood cells, white blood cells, and platelets
  • Polycythemia vera: Disorder where the body overproduces red blood cells
  • Primary myelofibrosis: Excess scar tissue forms in the bone marrow and disrupts normal blood cell production
  • Essential thrombocythemia: The body produces excess platelets, resulting in clotting and abnormal bleeding
  • Chronic neutrophilic leukemia: Bone marrow cells that produce blood cells develop and function abnormally
  • Chronic eosinophilic leukemia: Too many eosinophils, a type of white blood cell, are found in the bone marrow and blood

Risk factors for Developing a Myeloproliferative Neoplasm Disorder

Things that increase your risk of developing a Myeloproliferative Neoplasm disorder include:

  • Intense exposure to radiation
  • Exposure to certain chemicals, such as benzene or toluene
  • Exposure to electrical wiring
  • Having a mutation in the JAK2 gene is very common, which is a gene mutation that is acquired over time

Myeloproliferative Neoplasm Disorder Symptoms

Common symptoms for Myeloproliferative Disorder include:

  • Headache
  • Shortness of breath
  • Fatigue
  • Easy bruising or bleeding
  • Petechiae (red splotches under the skin)
  • Unexplained weight loss
  • Night sweats
  • Fever

Myeloproliferative Neoplasm Disorder Treatment Options

Treatment options for Myeloproliferative disorders vary depending on the type of disorder. Patients should consult their doctor to determine which treatment option is best for their cancer case, although common treatments include drug therapy and chemotherapies. Clinical trials are also a great option for those patients who have a Myeloproliferative disorder. Participation in a clinical trial may help advance cancer research, while also helping other patients who are experiencing the same disease. We can help patients find, qualify, and enroll into a clinical trial.


Our team of patient advocates can help guide you to treatment options you might not have been previously aware of. Although you might be new to cancer, we certainly are not. Navigating cancer patients through the tricky path of finding the best treatment is our goal. No two cancer patients are alike, which is why we find treatment for all of our patients based on their specific genomics, location, stage of cancer, and nearly 100 more data points.

    Learn Your Myeloproliferative Neoplasm
    Clinical Trial and Treatment Options